Name | (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-methanone dioxalate |
Synonyms | Dronedarone RC B (4-(3-(dibutylamino) (5-Amino-2-butylbenzofuran-3-yl) Des(Methylsulfonyl) Dronedarone Oxalate (5-AMino-2-butylbenzofuran-3-yl)(4-(3-(dibutylaMino)propoxy)phenyl)Methanone oxalate (5-aMino-2-butylbenzofuran-3-yl)(4-(3-(dibutylaMino)propoxy)phenyl)Methanone dioxalate (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-methanone dioxalate (5-aMino-2-butyl-3-benzofuranyl)[4-[3-(dibutylaMino) propoxy]phenyl]-Methanone dioxalate (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-methanone ethanedioate |
CAS | 500791-70-8 |
EINECS | 448-700-9 |
InChI | InChI=1/C30H42N2O3.2C2H2O4/c1-4-7-11-28-29(26-22-24(31)14-17-27(26)35-28)30(33)23-12-15-25(16-13-23)34-21-10-20-32(18-8-5-2)19-9-6-3;2*3-1(4)2(5)6/h12-17,22H,4-11,18-21,31H2,1-3H3;2*(H,3,4)(H,5,6) |
Molecular Formula | C32H44N2O7 |
Molar Mass | 568.71 |
Melting Point | >165°C (dec.) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Beige |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Use | This product is for scientific research only and shall not be used for other purposes. |
Overview | (5-amino-2-butyl-3-benzofuryl)[4-[3-(dibutylamino) propoxy] phenyl] ketone dioxalate is an important intermediate for the synthesis of dronedarone hydrochloride. Dronedarone (Dronedarone), the chemical name is N-[2-n-butyl-3-[4-3-(di-n-butylamine) propoxy] benzoyl]-5-phenylprofuryl] Methanesulfonamide, developed by Sanofi-Avante, France, can effectively reduce atrial fibrillation or atrial flutter. It is an anti-arrhythmic drug suitable for patients with paroxysmal or persistent atrial fibrillation or atrial flutter. In July 2009, it was approved by the U.S. Food and Drug Administration (FDA) for listing. |